Chapter 8 Group Sequential Designs

https://rinpharma.shinyapps.io/gsdesign/ https://arxiv.org/pdf/2303.01040.pdf https://www.rpact.org/vignettes/planning/rpact_boundary_examples/ gsDesign

8.1 Group Sequential Designs

8.2 Power & Sample Size Calculations

8.3 Analyses: Unadjusted and Adjusted